The hard truth is that it is through normal PC usage, such as when you install or uninstall an application, update your OS, or connect new devices. Now, you may begin to wonder how these issues occur in the first place. For example, have you found File explorer not responding in Windows? This is one of possible malfunctions. Yet, other malfunctions can be extremely complicated to the extent of rendering your computer unusable. Some registry abnormalities, such as empty keys, are no issue at all until they begin to accumulate over time. So you can see how corrupt or broken entries in the registry can adversely affect the whole system